Book excerpt: Healthcare and knowledge management is the need of the era; this book investigates various challenges faced by practitioners in this area. It also covers the work to be done in the healthcare sector and the use of different computing techniques for better insight and decision-making. Healthcare and Knowledge Management for Society 5.0: Trends, Issues, and Innovations showcases the benefits of computing techniques used for knowledge management in the field of healthcare in the futuristic perspective of having a human-centric society 5.0. The book includes topics related to the use of technologies like artificial intelligence, machine learning, deep learning, Internet of Things, blockchain, and sensors for effective healthcare and management. Case studies are included for easy comprehension and the book covers the most up-to-date research in the field. The use of techniques like artificial intelligence in the field of knowledge management is also discussed. This book is intended for researchers and academicians to explore new ideas, techniques, and tools. Researchers working in interdisciplinary research can also find many interesting topics which will pave the way for a new arena in healthcare and knowledge management.