Book excerpt: 2 DANNY D. REIBLEI AND KATERINA DEMNEROVA 1 Hazardous Substance Research Center/South and Southwest, Louisiana State University, Baton Rouge, LA 70803 2 Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague, Czech Republic On May 24, 2001, a total of 102 students and lecturers participated in an Advanced Study Institute (ASI) sponsored by the North Atlantic Treaty Organization (NATO) under our direction. The Institute was focused on in situ and onsite management of contaminated sites. The objective of the Institute was to balance state of the art science with techniques for field application of a variety of technologies for in situ assessment and remediation of contaminated sites. Many of the lecturers were drawn from the ranks of the Hazardous Substance Research Centers, multi-university consortia that have been funded by the US Environmental Protection Agency to conduct research and technology transfer designed to promote risk-based management and control of hazardous substances for the nation. The Centers have made special contributions to the areas of in situ and onsite assessment and remediation of contaminated sites. Such approaches have the potential for being significantly less expensive than other assessment and remediation approaches while maintaining accuracy and effectiveness. Cost-effective remedial and management approaches that are also effective in minimizing exposure and risk to human health and the environment are a critical need throughout the world but particularly in Eastern Europe and the former Soviet Union where resources that can be devoted to environmental cleanup are especially limited.