Book excerpt: The FAO Regional Initiative on Water Scarcity (WSI), initiated in 2013, identified that lack of water resources is a potential disaster scenario for the Near East and North Africa (NENA) region. The WSI initiative developed out of 31st Session of the FAO Near East and North Africa (NENA) Regional Conference held in Rome in May 2012, outcomes from the Hyogo Framework Agreement 2005 – 2015, and highlighted through work undertaken by the Arab Water Council in reports in 2004, 2012 and 2015. Several projects were started, including use of non-conventional water resources in integrated agriculture - aquaculture (IAA) systems within the NENA region. Agriculture is the largest food production type in the region and the highest water use. Aquaculture production is also a major food sector and development of integrated systems, for increase productivity and to reduce overall water use in food production, is a useful approach. Water scarcity is particularly acute in arid regions of the NENA region, and is a finite resource, with IAA competing for water with other large sectors including domestic and industrial use. Non-conventional water resources are identified as a potential resource to develop IAA systems in a more unified way, reducing the burden of use on standard renewable water resources. The principle objective of the work was to build broad partnerships to support greater understanding in implementation and use of non-conventional water resource in IAA systems.