Book excerpt: This book examines the manufacturing, supply chain and product-level sustainability of leather and footwear products. This book deals with the environmental and chemical sustainability aspects pertaining to the tanning supply chain and the related mitigation measures. The book also explores interesting areas of leather and footwear sustainability, such as waste & the 3R’s and their certification for sustainability. At the product level, the book covers advanced topics like the circular economy and blockchain technology for leather and footwear products and addresses innovation development and eco-material use in footwear by investigating environmental sustainability and the use of bacterial cellulose, a potential sustainable alternative for footwear and leather products.