Search Results

Membrane Protein Protocols

Download or Read eBook Membrane Protein Protocols PDF written by Barry S. Selinsky and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 330 pages. Available in PDF, EPUB and Kindle.
Membrane Protein Protocols
Author :
Publisher : Springer Science & Business Media
Total Pages : 330
Release :
ISBN-10 : 9781592594009
ISBN-13 : 159259400X
Rating : 4/5 (09 Downloads)

Book Synopsis Membrane Protein Protocols by : Barry S. Selinsky

Book excerpt: Knowledge of the three-dimensional structure of a protein is absolutely required for the complete understanding of its function. The spatial orientation of amino acids in the active site of an enzyme demonstrates how substrate specificity is defined, and assists the medicinal chemist in the design of s- cific, tight-binding inhibitors. The shape and contour of a protein surface hints at its interaction with other proteins and with its environment. Structural ana- sis of multiprotein complexes helps to define the role and interaction of each individual component, and can predict the consequences of protein mutation or conditions that promote dissociation and rearrangement of the complex. Determining the three-dimensional structure of a protein requires milligram quantities of pure material. Such quantities are required to refine crystallization conditions for X-ray analysis, or to overcome the sensitivity limitations of NMR spectroscopy. Historically, structural determination of proteins was limited to those expressed naturally in large amounts, or derived from a tissue or cell source inexpensive enough to warrant the use of large quantities of cells. H- ever, with the advent of the techniques of modern gene expression, many p- teins that are constitutively expressed in minute amounts can become accessible to large-scale purification and structural analysis.


Membrane Protein Protocols Related Books

Membrane Protein Protocols
Language: en
Pages: 330
Authors: Barry S. Selinsky
Categories: Science
Type: BOOK - Published: 2008-02-03 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

Knowledge of the three-dimensional structure of a protein is absolutely required for the complete understanding of its function. The spatial orientation of amin
Membrane Protein Purification and Crystallization
Language: en
Pages: 339
Authors: Carola Hunte
Categories: Science
Type: BOOK - Published: 2003-01-05 - Publisher: Elsevier

DOWNLOAD EBOOK

This second edition of Membrane Protein Purification and Crystallization, A Practical Guide is written for bench scientists working in the fields of biochemistr
Production of Membrane Proteins
Language: en
Pages: 631
Authors: Anne Skaja Robinson
Categories: Science
Type: BOOK - Published: 2011-06-15 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

Designed as a research-level guide to current strategies and methods of membrane protein production on the small to intermediate scale, this practice-oriented b
Biophysics of Membrane Proteins
Language: en
Pages: 0
Authors: Vincent L. G. Postis
Categories: Science
Type: BOOK - Published: 2021-02-14 - Publisher: Humana

DOWNLOAD EBOOK

This volume provides recent advances in the field of biophysics of membrane proteins. Chapters are divided into several parts: detailing biochemistry and functi
Expression, Purification, and Structural Biology of Membrane Proteins
Language: en
Pages: 423
Authors: Camilo Perez
Categories: Science
Type: BOOK - Published: 2021-03-14 - Publisher: Humana

DOWNLOAD EBOOK

This book collects up-to-date advanced protocols and advice from leading experts in the area of membrane protein biology that can be applied to structural and f
Scroll to top