Book excerpt: Metabolic Inhibitors: A Comprehensive Treatise, Volume III reviews developments in metabolic and enzyme inhibition. With contributions by investigators experienced in their respective fields, the book explores metabolic processes or systems and covers topics ranging from membrane transport to immunization; gene activity; DNA, RNA, and protein syntheses; photosynthesis; lipid metabolism; and blood clotting. Organized into 12 chapters, this volume begins with an overview of transport reactions and their inhibition, emphasizing inhibitors of ATPase including cations, substrates, and products. Some chapters deal with inhibitors, such as antibiotics; polypeptide and protein hormones; modified transfer RNAs; and oligonucleotides. Other chapters discuss inhibitors of immune reactions; animal virus replication; plant viruses and mycoplasma; and isozymes. An account of genetic deletions is also given. Finally, the book considers molecules that act as repressors and derepressors of gene activity. This book will be beneficial to biochemists and medical research workers, as well as to virologists, microbiologists, plant physiologists, and agronomists.