Book excerpt: The first textbook that focused on the multidisciplinary treatment of migraine including pharmacological and non-pharmacological approaches. This comprehensive text discusses epidemiology, pathophysiology, diagnosis, and management of patients with migraine headache integrating clinical experience and expertise with current evidence-based best practices. The authors are worldwide experts recognized in migraine and headache with experience in academic, research, and practice settings. This book reviews the options for medical management of patients with migraine by way of: pharmacological interventions; musculoskeletal interventions including muscle and joint.centered interventions, manual therapy, and dry needling; and complementary and alternative medicine techniques including naturopathy, acupuncture, and placebo. With a multimodal and multidisciplinary approach, this comprehensive resource provides a variety of therapeutic tools for students and practitioners to provide excellent care and medical management of patients with migraine headache