Book excerpt: This book explores the enormous diversity in social perspectives on the emergence of nanoscale sciences and technologies. It points to four nodes of interest where nano meets macro: in the making, in the public eye, in the big questions, and in the tough decisions. Each node draws attention to important lines of research and pertinent issues. The book is designed for interdisciplinary teaching, but the richness of issues and perspectives makes it of interest to all researchers, practitioners, and non-academics wanting an introduction to social perspectives on nanoscale sciences and technologies.