Book excerpt: This book discusses all the major nature-inspired algorithms with a focus on their application in the context of solving navigation and routing problems. It also reviews the approximation methods and recent nature-inspired approaches for practical navigation, and compares these methods with traditional algorithms to validate the approach for the case studies discussed. Further, it examines the design of alternative solutions using nature-inspired techniques, and explores the challenges of navigation and routing problems and nature-inspired metaheuristic approaches.