Book excerpt: This book offers clinical physicians and plastic surgeons a detailed and comprehensive overview of the nonsurgical techniques used for rejuvenation of the lips and eyes. A key aim is to provide practical guidelines for patient selection in order to optimize the choice of treatment in different circumstances. These guidelines will assist in ensuring that the selected rejuvenation technique and the number of applications are appropriate to the specific disorder being treated, thereby maximizing benefits and minimizing side effects. The book explains pretreatment evaluation and describes a wide variety of rejuvenation techniques, including the use of hyaluronic acid fillers, botulinum toxins, skin needling, chemical peels, radiofrequency, ultrasound, and fractional lasers (ablative and nonablative). Contraindications to and complications of the various treatments are clearly identified. A notable feature is the emphasis placed on the role of combined treatments and how they can work in a complementary way to deliver optimal outcomes. The integrated, less invasive approach to periorbital and lip rejuvenation described here by acknowledged experts in the field will enable practitioners to choose with confidence the best aesthetic procedures and innovative tools for their patients.