Book excerpt: This book aims to provide readers with a sound understanding of the spectrum of radiologic appearances of bone tumors, which reflect histopathology, and the pattern analysis of imaging findings.The first part of the book explains basic concepts and diagnostic parameters, including demographics, lesion location, biological activity, matrix mineralization, and endosteal and periosteal reactions. In the second part, typical and atypical radiologic features of bone tumors are reviewed in detail, with emphasis on the characteristic radiographic and MR imaging findings and reference to schematic drawings and pathologic or operative images when appropriate.The third part focuses on problem solving in cases encountered in real radiology practice and identifies categorical patterns on the basis of radiographic and MR variables and lesion location. Informative cases are illustrated and compared to enhance understanding of differential diagnosis using pattern analysis. The final part of the book helps readers to consolidate what they have learned and to hone their diagnostic reasoning skills by presenting about 30 typical bone tumor cases with questions, answers, and commentary.