Book excerpt: Pattern-Focused Therapy incorporates brief cognitive behavioral therapy (CBT) interventions for symptom reduction and a step-by-step therapeutic strategy for effectively changing clients’ maladaptive patterns and increasing their well-being. Integrating research, clinical expertise, and client needs and values, Pattern Focused Therapy is a highly effective third-wave CBT approach that can be applied to a wide range of clients. This text guides therapists through the pattern focused approach, facilitating learning through session-by-session transcriptions and commentaries from the first to the final session. Interventions for optimizing treatment and indicators of successful therapy are included along with a chapter on Pattern Focused Therapy in integrated care settings. Seasoned and beginner therapists alike will benefit from this invaluable method for learning and mastering this evidence-based approach.