Book excerpt: Completely revised and updated for 2015, the Physicians' Cancer Chemotherapy Drug Manual is an up-to-date guide to the latest information on standard therapy and recent advances in the field. Written by world-class experts in clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens--both on- and off-label--for the treatment of all the major cancers. SPECIAL FEATURES: -Revised to reflect rapid advances in the field, incorporating treatment strategies and new drugs like afatinib, ceritinib, ibrutinib, idelalisib, obinutuzumab, and ramucirumab. -A specific chapter focused on profiling antiemetic drugs and antiemetic treatment regimens. -Diagrams of drug structures and pathways for many of the agents. -Offers a comprehensive discussion of clinical pharmacology, special considerations, indications, and dosages. -Covers toxicity and drug-drug interactions. -A section on chemotherapy regimens for all major cancers. -Provides an overview of the basic principles of cancer drug therapy.