Book excerpt: This volume provides a comprehensive overview on developmental origins of health and disease regarding various factors related to the origins of non-communicable diseases (NCDs) from early life. It offers a summary of the impacts of various factors such as epigenetics; gene-environment interaction; ethnic predisposition to NCDs and their risk factors; prenatal factors; fetal programming; maternal weight status and weight gain during pregnancy; type of feeding during infancy; growth pattern during childhood; obesity; stunting; socioeconomic status; dietary and physical activity habits; as well as environmental factors including air pollution and global climate change on the development and progress of NCDs.