Book excerpt: Principles of Multiple-Liquid Separation Systems: Interaction, Application and Advancement describes the basic principles and advancements of multiple-liquid separation systems in downstream processing. Several important elements are included, such as the fundamental process and mechanisms of the multiple-liquid separation system, key principles of the interaction between different solvents and phase components, applications, and green solvents for the separation system. Furthermore, the book gives insights in commercializing this separation technique to industrial scale and making the process environmentally and economically sustainable. The book also presents constructive critics of this separation technique for both past and the latest findings. - Comprehensively reviews several advanced separation methods and their fundamentals in a single source - Covers a deep understanding of the interaction between various liquid phase techniques and the latest cases of advanced techniques applied in bioprocesses - Provides a critical and constructive judgement of costs and environmental sustainability of multiple-liquid separation systems