Book excerpt: This is an open access book. Homeostasis is upset by stress, which also triggers an adaptive reaction that shields an organism from harm. High allostatic load, on the other hand, might result from excessive stress or stress during a sensitive time, which eventually promotes or hastens maladaptive processes. Adverse childhood experiences, often known as ACEs, are early life stresses that individuals endure and are linked to the development of behavioural abnormalities and psychiatric problems in adulthood. Furthermore, there is evidence that people with early life stress have a more severe illness course and are less receptive to treatment for mood and anxiety disorders like depression. Stress throughout early childhood is linked to a modification of the brain's developmental trajectory, which can result in long-lasting behavioural alterations, but the consequences of stress in adulthood can be temporary and reversible. Behaviour problems brought on by ELS exposure can start in adulthood or during childhood or adolescence. A developing field of research, neuroscience, is expanding quickly. Neurology, psychiatry, and psychology are necessary for a deeper understanding of it. The purpose of this conference is to inform attendees of the most recent developments in the field of neuroscience education. The Faculty of Medicine at Universitas Sumatera Utara is hosting the 6th International Conference on Neuroscience, Neurology, and Psychiatry (ICoNaP) 2023 with the theme "The impact of early life stress on the neuroscience field" for psychiatrists, neurologists, general practitioners, and other interested specialists. Since 2018, ICoNAP has occurred annually. Speakers from many different nations are invited to the conference, both nationally and internationally. The committee has elected speakers from Malaysia, Singapore, Germany, Australia, India, Thailand, the United States, France, and Malaysia over the years. This year's conference will be hosted virtually and will have speakers from Singapore, Malaysia, the United Kingdom, Japan, Australia, and Singapore. Researchers and specialists in the fields of neuroscience, neurology, and psychiatry can exchange ideas, experiences, and insights during the conference. Case studies and articles will have the opportunity to be published in international publications, and 920 researchers and professionals have so far taken part in previous ICoNAPs. More than 100 articles and case studies have also been released.