Book excerpt: Psychological Support by Cognitive Behavioral Therapy for Cri du Chat Syndrome was written to provide a holistic and supportive guide for families, caregivers, and professionals working with individuals affected by Cri du Chat syndrome. This rare genetic disorder, characterized by a spectrum of physical and cognitive challenges, often places a profound emotional and psychological strain not only on those diagnosed but also on their families and caregivers. The complex nature of Cri du Chat syndrome requires a multidimensional approach that addresses both medical and psychological needs, with a strong emphasis on mental health and resilience. This book combines insights from genetics, psychology, and Cognitive Behavioral Therapy (CBT) to create a toolkit for navigating the unique challenges of Cri du Chat syndrome. Beginning with an introduction to genetics and hereditary conditions, the book aims to foster an understanding of the biological underpinnings of the disorder. From there, readers are guided through the principles of CBT—a highly effective therapeutic approach that empowers individuals to manage their thoughts, emotions, and behaviors in adaptive ways. By integrating CBT techniques into the lives of those affected by Cri du Chat syndrome, we can address the emotional challenges that arise, from anxiety and fear of social stigma to frustration with treatment limitations. To make this resource as practical as possible, each section is designed with actionable strategies and specific CBT tools tailored to common emotional and physical concerns encountered by individuals with Cri du Chat syndrome. Topics such as coping with chronic pain, managing social interactions, and building self-esteem are presented alongside techniques for therapists, caregivers, and family members to apply in their daily lives. This book is not only a guide for therapeutic techniques but also a compassionate companion for those navigating the complexities of Cri du Chat syndrome. It emphasizes hope, resilience, and the importance of mental well-being as a vital part of the journey. I hope this resource serves as both an educational tool and a source of encouragement, helping readers build a supportive and nurturing environment for those affected by Cri du Chat syndrome. Thank you for joining me in this mission to provide psychological support for individuals with Cri du Chat syndrome. May this book be a step towards fostering understanding, resilience, and emotional strength for all those on this journey.