Book excerpt: This book presents state-of-the-art research on responsible operations practices. The book identifies the challenges and opportunities arising from the shift towards responsible business operations and examines these issues through the lenses of operations management, emphasizing the supply chain transformations associated with these changes. Developing a responsible business model presents a great opportunity for firms to differentiate in the marketplace through innovative models and insights around responsible operations and supply chain management. To do so, companies in many industries are changing their practices around sourcing materials, supplier compliance around processes and labor, scientific and sustainable approaches to farming in emerging countries, managing counterfeiting risks, and public health management. Responsible Business Operations: Challenges and Opportunities is divided into three sections. Section 1 focuses on environmental responsibility for companies. It also explores alternative energy solutions for both the developed and developing world, as well as worldwide carbon footprint reduction efforts. Section 2 is dedicated to social responsibility, with chapters covering topics including improving agricultural food chains and humanitarian challenges for businesses. Finally Section 3 promotes ethical responsibility, analyzing ways to improve supplier compliance to product, process and ethical standards.