Book excerpt: An in-depth, accessible study of school based intervention programs that affect girls in Kenya, South Africa and Zimbabwe, as a representative subset of Sub Saharan Africa. This book indulges in the reasons why HIV goals are lagging behind particularly with adolescent girls and young women. It tackles issues such as access to quality HIV education and delivery methods used by teachers. It discusses culture and religion as barriers to HIV education. It concludes by suggesting ways for a multi-sectoral approach and transformational change in order to reach the Sustainable Development Goals 2030 and the 90-90-90 targets.