Book excerpt: Smart Nanomaterials to Combat the Spread of Viral Infections comprises nanotechnology-based approaches with detailed preventive and treatment methodology for enabling their application in antiviral systems. This book discusses the role of metal nanoparticles in the treatment of and prevention of viral infections and nanotechnology advancements in antiviral coatings to combat affected surfaces. It also covers the use of nanomaterials for the efficient intracellular delivery of antiviral agents to disinfect and treat viral infections. This is a timely coverage of how nanotechnologies and materials as well as the utilization of artificial intelligence and Internet of things–based smart nano-systems are used to control and manage viral infections during the COVID-19 pandemic. Advances in smart research and future antimicrobial applications round out the book. This book provides a comprehensive overview of smart nanomaterials and advanced nano-system applications to researchers and academics in virology, microbiology, chemistry, material science, nanotechnology, and biotechnology as well as those in industries interested in their virucidal properties to prevent viral infections. - Encompasses the novel synthesis of nanostructures and cost-effective nanosystems from functional hybrid materials with special emphasis on their effective virucidal properties being biocompatible and economic - Examines mechanisms of advanced nanomaterials as effective virucidal agents in disinfectants, coatings, treatment, and preventive approaches - Discusses possible advancements and upcoming smart research in antimicrobial applications - Offers timely coverage of SARS-CoV-2 pandemic management strategies