Book excerpt: This Special Edition aims to complement State of the Nordic Region 2020 by taking an in-depth look at some of the factors that contribute to wellbeing and health in the Nordic Region, and exploring how digitalisation in health care and social care can contribute to wellbeing. The report illustrates the central role of demography, whereby the composition and the spatial patterns of the population together with socio-economic factors contribute to shaping the living conditions and wellbeing in different parts of the Nordic Region. Despite a general pattern of urban regions being richer, more well educated and living longer, we also find many thriving rural areas attracting new young residents. Digital infrastructure plays a crucial role for the development of those rural areas.