Book excerpt: The response to the environmental and internal stimuli is one of the basic characteristics of living organisms. Inspired by this natural strategy and fast developing nanotechnology and materials science, currently, stimuli-responsive nanomedicine emerges as an active and important field of nanomedicine. This book offers a fundamental and comprehensive overview of stimuli-responsive nanomedicine, and also compiles and details its recent cutting-edge findings and most impressive achievements in biomedical applications, from a pharmaceutical science perspective, making it the first book in this field. By providing readers a broad and in-depth coverage of endogenous and exogenous stimuli as well as their applicable nanomedicines, this book is valuable for students, researchers, and educators in biomedical sciences or anyone interested in this burgeoning field.