Book excerpt: The book contains the newest advances related to research and development of complex intellectual systems of various nature, acting under conditions of uncertainty and multifactor risks, intelligent systems for decision-making, high performance computing, state-of-the-art information technologies for needs of science, industry, economy, and environment. The most important problems of sustainable development and global threats estimation, forecast and foresight in tasks of planning and strategic decision-making are investigated. This monograph will be useful to researchers, post-graduates, and advanced students specializing in system analysis, decision-making, strategic planning or engineering design, fundamentals of computational Intelligence, artificial Intelligence systems based on hybrid neural networks, big data, and data mining.