Book excerpt: This book examines when, where, how, and why artificial intelligence and digital transformation can boost innovation and transform the economy, society and democracy. It is developed based on the Cyber-D4 nexus, which is a conceptual framework of Cyber-Defense, Cyber-Development, Cyber-Democracy, and Cyber-Diplomacy. This nexus ties new national and industrial cyber strategies, including business strategies for smart cities and the Internet of Things, with the local, national, regional, and global security and economic objectives.