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The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Do

Genetics and Neurobiology of Down Syndrome provides a thorough review of the genetic etiology and mechanisms of trisomy 21. The author discusses the history of

Unique, up-to-date and comprehensive, this book considers in depth the remarkable association between Down Syndrome and Alzheimer disease. It provides overviews

It was Oscar Wilde who defined the tragedy of old age by saying that " . . . as soon as you are old enough to know better, you don't know anything at all. " As

Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of