Book excerpt: Extraordinary advances in neurochemistry are both transforming our understanding of human nature and creating an urgent problem. Much is now known about the ways that neurotransmitters influence normal social behavior, mental illness, and deviance. What are these discoveries about the workings of the human brain? How can they best be integrated into our legal system? These explosive issues are best understood by focusing on a single neurotransmitter like serotonin, which is associated with such diverse behaviors as dominance and leadership, seasonal depression, suicide, alcoholism, impulsive homicide, and arson. This book brings together revised papers from a conference on this theme organized by the Gruter Institute for Law and Behavioral Research, supplemented with articles by leading scholars who did not attend. Contributors include psychiatrists, neurologists, social scientists, and legal scholars. The Neurotransmitter Revolution presents a unique survey of the scientific and legal implications of research on the way serotonin combines with other factors to shape human behavior. The findings are quite different from what might have been expected even a decade ago. The neurochemistry of behavior is not the same thing as genetic determinism. On the contrary, the activity of serotonin varies from one individual to another for many reasons, including the individual’s life experience, social status, personality, and diet. And there are a number of major neurotransmitter systems, each of which interacts with the other. Behavior, culture, and the social environment can influence neurochemistry along with inheritance. Nature and nurture interact—and these interactions can be understood from a vigorously scientific point of view. The fact that our actions are heavily influenced by neurotransmitters like serotonin is bound to be disquieting. A sophisticated understanding of law and human social behavior will be needed if our society is to respond adequately to these rapid advances in our knowledge. This book is an essential step in that direction, providing the first comprehensive survey of the biochemical, social, and legal considerations arising from research on the behavioral effects of serotonin and related neurotransmitters.