Book excerpt: The world tilapia aquaculture production grew from 380 000 tonnes in 1990 to 6 million tonnes in 2018, making it the fourth-largest species group in global aquaculture. Tilapias are the second-largest species group in Mexico’s aquaculture with its 53 000 tonnes of production contributing to around 20 percent of the 247 000 tonnes of total aquaculture production in 2018. Mexico is the second-largest tilapia capture fisheries country, and its 116 000 tonnes of tilapia capture fisheries production in 2018 was primarily contributed by culture-based fisheries. Overall, Mexico is the second-largest international market for tilapia products, and the 228 000 tonnes live weight equivalent of its tilapia import in 2018 was higher than its domestic production. The average per capita apparent tilapia consumption in Mexico was 3.08 kg (21 percent of its total fish consumption) in 2018, which was much higher than the 0.9 kg world average. This document assesses tilapia farming and the value chain in Mexico by examining tilapia farming systems and practices, dissecting the tilapia value chain, evaluating the sector’s social and economic performance, discussing the impacts of proper governance and institutions on the sector development, and highlighting potentials, issues, constraints and challenges in the development of tilapia farming or aquaculture in general. The document ends with a brief discussion of the impacts of the ongoing coronavirus disease 2019 pandemic on the tilapia industry in the country.