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Virus Discovery by Metagenomics: The (Im)possibilities

Download or Read eBook Virus Discovery by Metagenomics: The (Im)possibilities PDF written by Bas E. Dutilh and published by Frontiers Media SA. This book was released on 2017-10-25 with total page 218 pages. Available in PDF, EPUB and Kindle.
Virus Discovery by Metagenomics: The (Im)possibilities
Author :
Publisher : Frontiers Media SA
Total Pages : 218
Release :
ISBN-10 : 9782889453085
ISBN-13 : 2889453081
Rating : 4/5 (85 Downloads)

Book Synopsis Virus Discovery by Metagenomics: The (Im)possibilities by : Bas E. Dutilh

Book excerpt: Since the late 1800s, the discovery of new viruses was a gradual process. Viruses were described one by one using a suite of techniques such as (electron) microscopy and viral culture. Investigators were usually interested in a disease state within an organism, and expeditions in viral ecology were rare. The advent of metagenomics using high-throughput sequencing has revolutionized not only the rate of virus discovery, but also the nature of the discoveries. For example, the viral ecology and etiology of many human diseases are being characterized, non-pathogenic viral commensals are ubiquitous, and the description of environmental viromes is making progress. This Frontiers in Virology Research Topic showcases how metagenomic and bioinformatic approaches have been combined to discover, classify and characterize novel viruses.


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